Ability to type in a path for File Manager for convenience
 

Typing makes it a little easier. Also, using config files, if I were to change the default directories, does it mess up any other settings? Like does this program have to use the myusername/data portion of the path: /var/www/myusername/data/www/example.org ??

The whole structure of directories is created, taking into account the security system so that users of one site could not get to other sites

Change the path /var/www in a CentOS Linux system is not possible, because these parameters are strictly for web-server apache, and will not work then the CGI-scripts

But all these pathes are configurable, see ISPmanager documentations, parameters in the ISPmanager config file (Advanced configuration)

Thanks for the information Slava.